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Evaluating the Control Banding Nanotool: a qualitative risk assessment method for controlling nanoparticle exposures

机译:评估控制带纳米工具:用于控制纳米粒子暴露的定性风险评估方法

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摘要

Control banding (CB) strategies offer simplified processes for controlling worker exposures in the absence of firm toxicological and exposure information. The nanotechnology industry is an excellent candidate for applying such strategies with overwhelming uncertainties of work-related health risks posed by nanomaterials. A recent survey shows that a majority of nanomaterial producers are not performing a basic risk assessment of their product in use. The CB Nanotool, used internationally, was developed to conduct qualitative risk assessments to control nanoparticle exposures. Nanotoxicology experts have requested standardization of toxicological parameters to ensure better utility and consistency of research. Such standardization would fit well in the CB Nanotool’s severity and probability risk matrix, therefore enhancing the protection of nanotechnology industry workers. This article further evaluates the CB Nanotool for structure, weighting of risk factors, and utility for exposure mitigation, and suggests improvements for the CB Nanotool and the research needed to bolster its effectiveness.
机译:在没有确切的毒理学和暴露信息的情况下,控制带(CB)策略为控制工人的暴露提供了简化的过程。纳米技术行业是应用此类策略的绝佳人选,而这种策略具有由纳米材料构成的与工作相关的健康风险的绝大多数不确定性。最近的一项调查显示,大多数纳米材料生产商并未对其使用中的产品进行基本风险评估。国际上使用的CB Nanotool是为了进行定性风险评估以控制纳米颗粒的暴露而开发的。纳米毒理学专家要求对毒理学参数进行标准化,以确保更好的效用和研究的一致性。这样的标准化非常适合CB Nanotool的严重性和概率风险矩阵,因此可以增强对纳米技术行业工人的保护。本文进一步评估了CB纳米工具的结构,风险因素的权重以及减轻接触的效用,并提出了CB纳米工具的改进以及增强其有效性的研究。

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