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Processing, characterization and biological testing of porous titanium obtained by space-holder technique

机译:用空间保持器技术获得的多孔钛的加工,表征和生物学测试

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摘要

The high Young’s modulus of titanium with respect to that one of the bone is the main cause of the stress-shielding phenomenon, which promotes bone resorption around implants. Development of implants with a low Young’s modulus has gained increased importance during the last decade, and the manufacturing of porous titanium is one of the routes to reduce this problem. In this work, porous samples of commercially pure titanium grade IV obtained by powder metallurgy with ammonium bicarbonate (NH4HCO3) as space-holder were studied. Evaluations of porosity and mechanical properties were used to determine the influence of compaction pressure for a fixed NH4HCO3 content. Measurements by ultrasound tests gave Young’s modulus results that were low enough to reduce stress shielding, whilst retaining suitable mechanical strength. Biological tests on porous cp Ti showed good adhesion of osteoblasts inside the pores, which is an indicator of potential improvement of osteointegration.
机译:钛相对于骨头之一的高杨氏模量是应力屏蔽现象的主要原因,该应力屏蔽现象促进了植入物周围的骨吸收。在过去的十年中,开发低杨氏模量的植入物变得越来越重要,而多孔钛的制造是减少这一问题的途径之一。在这项工作中,研究了以碳酸氢铵(NH4 HCO3 )为粉末载体通过粉末冶金获得的商业纯钛IV级多孔样品。通过孔隙率和力学性能评估来确定压实压力对固定NH4 HCO3 含量的影响。超声波测试得出的杨氏模量结果足够低,以减少应力屏蔽,同时保持适当的机械强度。对多孔cp Ti的生物学测试表明,成骨细胞在孔内具有良好的附着力,这是潜在的骨整合改善的指标。

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  • 来源
    《Journal of Materials Science》 |2012年第18期|p.6565-6576|共12页
  • 作者单位

    Department of Mechanical and Materials Engineering, E.T.S. de Ingeniería, Universidad de Sevilla, Avda. Camino de los Descubrimientos, s, 41092, Sevilla, Spain;

    Department of Mechanical and Materials Engineering, E.T.S. de Ingeniería, Universidad de Sevilla, Avda. Camino de los Descubrimientos, s, 41092, Sevilla, Spain;

    Biomaterials Research Group, Bioengineering Program, University of Antioquia, Medellín, Colombia;

    Biomaterials Research Group, Bioengineering Program, University of Antioquia, Medellín, Colombia;

    PECET, University of Antioquia, Medellín, Colombia;

    Departamento de Ingeniería Mecánica y de Materiales, Universidad Politécnica de Valencia, Camino de Vera s, 46022, Valencia, Spain;

    Biomaterials Research Group, Bioengineering Program, University of Antioquia, Medellín, Colombia;

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