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Production and characterization of HA and SiHA coatings

机译:HA和SiHA涂层的生产和表征

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摘要

Plasma sprayed hydroxyapatite (HA) coatings on metallic prostheses have been used clinically in dentistry and orthopedics since the mid 1980s. The coating properties are dependent on the spraying parameters. Since silicon-substituted hydroxyapatite (SiHA) has been shown to offer improved bioactivity over phase pure HA, SiHA coatings have the potential for enhanced performance in clinical application. In this study, phase pure HA and 0.8 wt% SiHA powders were synthesized with similar particle size distribution and morphology. The powders were plasma sprayed onto Ti-6Al-4V substrates at 37 kW and 40 kW plasma gun input power respectively. Four kinds of samples were prepared, HAC 37, HAC 40, SiHAC 37 and SiHAC 40. Materials characterization showed that the coatings were of relatively high phase purity. In vitro cell culture demonstrated that human osteoblast cells grew well on all samples, with the highest cell growth observed on SiHA coatings produced under the lower plasma gun input power.
机译:自1980年代中期以来,金属假体上的等离子喷涂羟基磷灰石(HA)涂层已在临床上用于牙科和骨科。涂层性能取决于喷涂参数。由于已证明硅取代的羟基磷灰石(SiHA)与纯HA相比具有更高的生物活性,因此SiHA涂层在临床应用中具有增强性能的潜力。在这项研究中,合成了具有相似粒度分布和形态的纯相HA和0.8 wt%SiHA粉末。将粉末分别以37 kW和40 kW等离子枪的输入功率进行等离子喷涂到Ti-6Al-4V基板上。制备了四种样品,HAC 37,HAC 40,SiHAC 37和SiHAC40。材料表征表明涂层具有较高的相纯度。体外细胞培养表明,人类成骨细胞在所有样品上均生长良好,在较低等离子枪输入功率下生产的SiHA涂层上观察到了最高的细胞生长。

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  • 来源
    《Journal of materials science》 |2010年第1期|173-181|共9页
  • 作者单位

    CCMM, Department of Materials Science and Metallurgy, University of Cambridge, Cambridge, UK;

    Orthopaedic Research Unit, University of Cambridge, Box 180, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK;

    Orthopaedic Research Unit, University of Cambridge, Box 180, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK;

    CCMM, Department of Materials Science and Metallurgy, University of Cambridge, Cambridge, UK;

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