EVALUATION OF NOVEL SOLID-PHASE EXTRACTION MICROSPHERES PREPARED BY A SURFACE IMPRINTING TECHNIQUE AND ITS APPLICATION TO THE SEPARATION OF DIETHYLSTILBESTROL FROM CHICKEN SAMPLES

摘要

A novel molecular imprinted solid-phase extraction technique was developed by using microspheres prepared by modifying the silica through a sol-gel process with a layer of homogeneous and compact molecularly imprinted polymer (MIP), which was synthesized with 3-aminopropyltriethoxysilane and phenyltrimethoxysilane as functional monomers, diethylstilbestrol (DES) as the template, and tetraethoxysilane as the cross-linker. The saturated adsorption capacity of the MIP under the condition of continuous loading of target solution was 0.213 mg g−1, and the imprinting factor reached 6.0. The selectivity factor of the MIPs for bisphenol A and 4-tert-butylphenol were 3.5 and 9.6, respectively. The molecular imprinted solid-phase extraction (MISPE) is a viable and efficient technique for extraction of DES from chicken samples with a recovery ofmore than 85%. The limit of detection (LOD) was determined to be 8 ng g−1.View full textDownload full textKeywordsdiethylstilbestrol, molecularly imprinted polymer, sol-gel, solid-phase extraction microsphereRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/10826076.2011.583374