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Effect of different cleaning processes on saponins’ loss rate and total ash clearance rate of Notoginseng and heavy metal health risk assessment

机译:不同清洗工艺对三七总皂苷损失率和总灰分清除率的影响及重金属健康风险评估

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摘要

Total ash clearance rates and saponins’ loss rates of Panax notoginseng rhizome, root tuber, andrnrootlet all increased with a prolonged washing time and the rising of water temperature. Underrnthe same conditions, the total ash clearance rates of fresh P. notoginseng were significantly higherrnthan those dried. Meanwhile, the saponins’ loss rates were opposite. The highest daily intake ofrnbioavailability heavy metals was rootlet. However, all of that was significantly lower than the recommendedrndaily intake, and both the target hazard quotients and hazard index values were lowerrnthan 1. Conclusion, it is effective to decrease washing time and water temperature in order tornreduce the loss of saponins of P. notoginseng on the premise that ash content of Notoginseng conformsrnto standard of Chinese Pharmacopeias. Safety risk assessments of heavy metals based onrnbioavailability can further reduce the health risk of the heavy metal exposure of Notoginseng.
机译:随着洗涤时间的延长和水温的升高,三七,根茎和根茎的总灰分清除率和皂苷的损失率均增加。在相同条件下,新鲜三七的总灰分清除率明显高于干燥三七。同时,皂苷的损失率却相反。生物利用度重金属的每日最高摄入量为根。但是,所有这些都大大低于推荐的每日摄入量,目标危险系数和危险指数均低于1。结论,有效减少洗涤时间和水温以减少三七的皂苷损失。在三七的灰分符合中国药典标准的前提下。基于生物利用度的重金属安全风险评估可以进一步降低三七的重金属暴露对健康的危害。

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  • 来源
    《Journal of Food Processing and Preservation》 |2018年第1期|e13409.1-e13409.10|共10页
  • 作者单位

    Yunnan Provincial Key Laboratory of Panaxnotoginseng, Key Laboratory of Panaxnotoginseng Resources SustainableDevelopment and Utilization of StateAdministration of Traditional ChineseMedicine, Kunming Key Laboratory ofSustainable Development and Utilization ofFamous-Region Drug, University BasedProvincial Key Laboratory of Screening andUtilization of Targeted Drugs, Kunming,Yunnan 650050, People’s Republic of China;

    Yunnan Provincial Key Laboratory of Panaxnotoginseng, Key Laboratory of Panaxnotoginseng Resources SustainableDevelopment and Utilization of StateAdministration of Traditional ChineseMedicine, Kunming Key Laboratory ofSustainable Development and Utilization ofFamous-Region Drug, University BasedProvincial Key Laboratory of Screening andUtilization of Targeted Drugs, Kunming,Yunnan 650050, People’s Republic of China;

    Institute of Chinese Materia Medica, ChinaAcademy of Chinese Medical Sciences,Beijing 100700, People’s Republic of China;

    College of Pharmacy, Hubei University ofChinese Medicine, Wuhan, Hubei 43065,People’s Republic of China;

    Yunnan Provincial Key Laboratory of Panaxnotoginseng, Key Laboratory of Panaxnotoginseng Resources SustainableDevelopment and Utilization of StateAdministration of Traditional ChineseMedicine, Kunming Key Laboratory ofSustainable Development and Utilization ofFamous-Region Drug, University BasedProvincial Key Laboratory of Screening andUtilization of Targeted Drugs, Kunming,Yunnan 650050, People’s Republic of China;

    Yunnan Provincial Key Laboratory of Panaxnotoginseng, Key Laboratory of Panaxnotoginseng Resources SustainableDevelopment and Utilization of StateAdministration of Traditional ChineseMedicine, Kunming Key Laboratory ofSustainable Development and Utilization ofFamous-Region Drug, University BasedProvincial Key Laboratory of Screening andUtilization of Targeted Drugs, Kunming,Yunnan 650050, People’s Republic of China;

  • 收录信息 美国《科学引文索引》(SCI);
  • 原文格式 PDF
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