EFFECT OF A ACTIVE INGREDIENT ON THE EXPRESSION OF BARRIER FUNCTION-RELATED GENES AND MOISTURISATION-RELATED PROTEINS

摘要

In conclusion, taken together, these results show that XG is able to regulate, at both gene and protein levels, the structural components and the metabolic regulators involved in epidermal differentiation. They also enlighten XG ability to regulate the main skin barrier function-related n etworks. Indeed, despite the differences between the two models (respectively 3D an d 2D ones) a nd between their respective treatment (topical application vs. culture medium), XG was able to regulate, at least partially, the same skin barrier and moisturizing function-related targets. In the future, further investigations on protein expression will be required to confirm its action on all these newly identified targets.