Synthesis, characterization and antimicrobial activity of five metal complexes of N -acetyl-9-hydroxyl-fluorene-9-hydrazide

摘要

Five mononuclear metal (Mn, Co, Ni, Cu, Zn) complexes have been prepared using a monoanionic tridentate ligand N-acetyl-9-hydroxyl-fluorene-9-hydrazidate (ahfhz−) and characterized by elemental analysis, ESI-MS, IR, UV, 1H NMR and 13C NMR. Antibacterial screening data showed that the cobalt and copper complexes and Hahfhz have moderate antimicrobial activity. The five metal complexes have some antagonistic effect against the ligand to Gram+ bacteria Staphylococcus aureus and Bacillus subtilis. The decrease in the efficiency of metal complexes may be assigned to the zero charge of the central core. [Co(ahfhz)₂]  · 2CH₃OH (3) crystallizes in monoclinic system with space group P2₁ , a  = 13.1379(7) à , b  = 17.7809(10) à , c  = 14.7403(8) à , β  = 110.0580(10)°; in the crystal structure packing N-H ··· O, O-H ··· O and C-H ···  π hydrogen bonding interactions lead to a supramolecular structure.View full textDownload full textKeywordsMetal complexes, N-acetyl-9-hydroxyl-fluorene-9-hydrazide, Crystal structure, Antimicrobial activityRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/00958970801914066