The serodiagnosis of infection with Salmonella typhi

摘要

Background/Aims-The serodiagnosis of infection with Salmonella typhi, using the Widal agglutination assay, relies on pa- Tients' antibodies to the O=9,12 lipopoly- Saccharide (LPS) antigens, H=d flagellar Antigens, and the Vi capsular antigens. A Vi aggultination titre of >1/40 has tra- Ditionally been regarded as indicative of Recent infection with S typhi. In this study, 91 sera were used to assess the reliability of the Widal aggultination assay based on antibodies to the Vi antigens.