Optimising testing for phospholipid antibodies

摘要

Aim-To compare anticardioplipin (ACL) and anti-β2 glycoprotein 1 (β2gp1) enzyme linked immunosorbent assays (ELISAs) in the diagnosis of antiphospholipid syn- drome (APS) and to incorporate these results into a meta-analysis of published data. Method-Three representative commer- Cial ACL ELISAs and an in house β2gp1 Assay were optimised and then assessed on 124 sera from normal donors, patients with infection, or patients with APS.