How many histological levels should be examined from tissue blocks originating in cone biopsy and large loop excision of the transformation zone specimens of cervix?

摘要

Aims-To establish the value of examining additional histological level sin cone bi- opsy and large loop excision of the transformation zone (LLETZ) specimens of cervix. Methods-Three deeper levels were exam- Ined form 200 consecutive cone bipsy and LLETZ specimens reported by a single Pathologist. Results-Examination of the first deeper Level resulted in cervical intraepithelial Neoplasia (CIN) being identified for the First time in five cases and in CIN1 being Upgrade din five more. Invasive cancer Was discovered in two cases that had Shown high grade CIN initially.