Expression of killer cell inhibitory recptors is restricted to true NK cell lymphomas and s subset of intestinal enteroapth-type T cell lymphomas with a cytotoxic phenotype

摘要

Background/Aims-Killer inibitory re- ceptors (KIR) have a modulating effect on the cytotoxic functions of natural killer (NK) cells and T cells. Because lymphoma cells often have the same receptors as their non-neoplastic counterparts, this study investigated the expression of KIR on well defined groups of NK and T cell lymphomas, with and without a cytotoxic phenotype, from different sites of origin.