Hepatitis G virus infection in lymphoma and in blood donors

摘要

Conclusions-The data suggest (1) that HGV is present in the normal blood donor Population; (2) that patients with lymph- Oma are at risk of acquiring HGV because Of their exposure to blood products; and (3) That persistent HGV infection does not Appear to cause serious liver disease in These patients. Aims-To determine whether the recently Described flavivirus, hepatitis G virus (HGV), might contribute to the pathogen- esis of lymphoma by testing for the presence of HGV RNA in sera from patients attending lymphoma clinics; to compare the incidence of HGV RNA in lymphoma patients with that in normal blood donors; and to look for potential risk factors for HGV infection and for evidence of hepatic disease in the HGV positive patients.