Daylight-driven photosensitive antibacterial melt-blown membranes for medical use

摘要

The application of long-lasting antibacterial microorganism materials has presented enormous challenges, especially when infection by pathogenic bacteria triggers global public health and safety issues. In this study, PPCL@PDA-TAEG melt-blown membranes with rechargeable, storable, and antibacterial property are constructed by grafting bisbenzophenone-structured 4,4,-terephthaloyl diphthalic anhydride photosensitizer and epigallocatechin gallate antibacterial agent on the PPCL melt-blown membranes. Result shows that after chemical grafting, the synergistic effects of rechargeable and antibacterial performance on the melt-blown membrane are achieved under ordinary daylight irradiation. Moreover, the resultant melt-blown membranes show enhanced chemical stability, and the UVevis absorption peak intensity remains above 80% after 1 month of storage under dark conditions. The sterilization rate of Staphylococcus aureus and Escherichia coli can reach 99.9% and 95%, respectively. The air permeability and moisture permeability of PPCL@PDA-TAEG melt-blown membranes are 22.3% and 43.7% higher, respectively, than those of PPCL melt-blown membranes. This facile and low-cost method for preparing PPCL@PDA-TAEG melt-blown membranes provides a new strategic direction for designing biomedical medical materials with long-lasting antibacterial efficacy. (c) 2021 Elsevier Ltd. All rights reserved.