Rapid Preparation of Monolithic Molecular Imprinted Polymer Fiber for Solid Phase Microextraction by Microwave Irradiation

摘要

In this paper, a simple, fast and in situ polymerization strategy to prepare monolithic molecularly imprinted polymer (MIP) fibers for solid phase microextraction (SPME) is developed using silica capillaries as molds. With the help of microwave irradiation, polymerization was carried out in 5.5 min using olivetol as a template molecular, a-methacrylic acid (MAA) as a functional monomer and ethylene dimethacrylate (EDMA) as a crosslinker, toluene and dodecanol as the binary porgens. The resulted MIP fibers were finally obtained after silica being etched away with a controlled length, and subsequently characterized by scanning electron microscope (SEM) and Fourier transform infrared absorption spectroscopy (FT-IR). Under the optimal extraction conditions, a simple method based on the coupling of MIP SPME with high performance liquid chromatography (HPLC) was used for the selective determination of the model mixtures of olivetol, phenol and m-toluidine in lake water and wheat bran samples. The recoveries of olivetol, phenol and m-toluidine for both samples were in the range of 87.3-93.6%, 21.4-27.2%, 18.9-24.8% at three spiked levels, respectively, demonstrating that higher extraction and the specific absorption occurred between the template molecule and the prepared MIP fiber.