Potential of α-amino alcohol p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, regarding its enantiomers

Shin-ichiro Masunaga; Koji Ono; Mitsunori Kirihata; Masao Takagaki; Yoshinori Sakurai; Yuko Kinashi; Tooru Kobayashi; Minoru Suzuki; Kenji Nagata; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori

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Potential of α-amino alcohol p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, regarding its enantiomers

机译：关于其对映异构体，α-氨基醇对硼硼苯丙氨醇在硼中子俘获治疗中作为硼载体的潜力

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We evaluated the potential of a newly developed 10B-containing α-amino alcohol of p-boronophenylalanine-10B (BPA), p-boronophenylalaninol (BPAol), as a boron carrier in boron neutron capture therapy.

机译：我们评估了一种新开发的含10 B的α-氨基醇的p-boronophenylalanine-10（BPA），p-boronophenylalaninol（BPAol）作为硼中子捕获中的硼载体的潜力。治疗。

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《Journal of Cancer Research and Clinical Oncology》 |2003年第1期|21-28|共8页
作者
Shin-ichiro Masunaga; Koji Ono; Mitsunori Kirihata; Masao Takagaki; Yoshinori Sakurai; Yuko Kinashi; Tooru Kobayashi; Minoru Suzuki; Kenji Nagata; Hideko Nagasawa; Yoshihiro Uto; Hitoshi Hori;
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作者单位

Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University;

Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University;

Department of Applied Biochemistry College of Agriculture Osaka Prefecture University;

Department of Neurosurgery Aino Junior College Hospital;

Division of Radiation Life Science Research Reactor Institute Kyoto University;

Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University;

Division of Radiation Life Science Research Reactor Institute Kyoto University;

Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University;

Radiation Oncology Research Laboratory Research Reactor Institute Kyoto University;

Department of Biological Science and Technology Faculty of Engineering University of Tokushima;

Department of Biological Science and Technology Faculty of Engineering University of Tokushima;

Department of Biological Science and Technology Faculty of Engineering University of Tokushima;

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正文语种 eng
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Neutron capture therapy; p-Boronophenylalaninol; Quiescent cell; Tirapazamine; Mild temperature hyperthermia;

机译：中子俘获疗法对苯硼苯丙氨酰静止细胞替拉帕明温和热疗;

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1. Potential of alpha-amino alcohol p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, regarding its enantiomers. [J] . Masunaga S, Ono K, Kirihata M, Journal of Cancer Research and Clinical Oncology . 2003,第1期

机译：就其对映异构体而言，α-氨基醇对-硼烷苯基丙氨醇在硼中子俘获治疗中作为硼载体的潜力。
2. Boronated Dipeptide Borotrimethylglycylphenylalanine as a Potential Boron Carrier in Boron Neutron Capture Therapy for Malignant Brain Tumors [J] . Masao Takagaki, Walda Powell, Anop Sood, Radiation Research: Official Organ of the Radiation Research Society . 2001,第1期

机译：硼化的二肽硼三甲基甘氨酰苯基丙氨酸作为硼中子捕获治疗恶性脑肿瘤的潜在硼载体。
3. 'Close-to-ideal' tumor boron targeting for boron neutron capture therapy is possible with 'less-than-ideal' boron carriers approved for use in humans [J] . RadiationPathologyDivisionDepartmentofRadiobiology Therapeutic delivery . 2015,第3期

机译：通过批准用于人类的“低于理想”的硼载体，可能将“接近理想”的硼靶向用于硼中子捕获疗法
4. Neutron capture therapy of murine melanoma on new boron carriers with use of capillary neutron optics [C] . G.I. Borisov, M.G. Naidenov, E.Yu. Koldaeva, International Conference on X-ray and Neutron Capillary Optics . 2005

机译：中子捕获在新硼载体上使用毛细胞中心光学捕获鼠马切撒瘤
5. Boron Neutron Capture Therapy for HER2+ breast cancers: A feasibility study evaluating BNCT for potential role in breast conservation therapies. [D] . Jenkins, Peter Anthony. 2012

机译：HER2 +乳腺癌的硼中子捕获疗法：评估BNCT在乳腺癌保护疗法中潜在作用的可行性研究。
6. Evaluation of the Potential of p‐Boronophenylalaninol as a Boron Carrier in Boron Neutron Capture Therapy Referring to the Effect on Intratumor Quiescent Cells [O] . Shin‐ichiro Masunaga, Koji Ono, Mitsunori Kirihata, 2001

机译：对硼中苯对苯丙氨酸作为硼载体在硼中子俘获治疗中的潜力评估涉及对瘤内静态细胞的影响
7. Evaluation of the Potential ofp-Boronophenylalaninol as a Boron Carrier in Boron Neutron Capture Therapy, Referring to the Effect on Intratumor Quiescent Cells [O] . Shin-ichiro Masunaga, Koji Ono, Mitsunori Kirihata, 2001

机译：评价硼中子捕获疗法中的硼硼苯酚作为硼载体的潜力，提及对肠静脉细胞的影响

Potential of α-amino alcohol p-boronophenylalaninol as a boron carrier in boron neutron capture therapy, regarding its enantiomers

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