Phase II clinical trial of advanced and metastatic gastric cancer based on continuous infusion of 5-fluorouracil combined with epirubicin and oxaliplatin

Xiaodong Zhu; Jiin Leaw; Weilie Gu; Yiying Qian; Hongyu Du; Biyun Wang; Xiaonan Hong; Jiliang Yin

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Phase II clinical trial of advanced and metastatic gastric cancer based on continuous infusion of 5-fluorouracil combined with epirubicin and oxaliplatin

机译：连续输注5-氟尿嘧啶联合表柔比星和奥沙利铂治疗晚期和转移性胃癌的II期临床试验

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Purpose To evaluate the efficacy and tolerability of systematic treatment of unresectable advanced or metastatic gastric cancer (A/MGC) based on EOF5 regimen (the combination of epirubicin, oxaliplatin and 5-day continuous infusion of 5-fluorouracil).

机译：目的评估基于EOF5方案（表柔比星，奥沙利铂和5天连续输注5-氟尿嘧啶的组合）无法手术切除的晚期或转移性胃癌（A / MGC）的系统治疗的疗效和耐受性。

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《Journal of Cancer Research and Clinical Oncology》 |2008年第9期|p.929-936|共8页
作者
Xiaodong Zhu; Jiin Leaw; Weilie Gu; Yiying Qian; Hongyu Du; Biyun Wang; Xiaonan Hong; Jiliang Yin;
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正文语种 eng
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Stomach neoplasms; Antineoplastic combined chemotherapy protocols; Adenocarcinoma; Therapeutic use; Fluorouracil; Epirubicin;

机译：胃肿瘤;抗肿瘤联合化疗方案;腺癌;治疗用途;氟尿嘧啶;表柔比星;

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1. Phase II clinical trial of advanced and metastatic gastric cancer based on continuous infusion of 5-fluorouracil combined with epirubicin and oxaliplatin. [J] . Zhu X, Leaw J, Gu W, Journal of Cancer Research and Clinical Oncology . 2008,第9期

机译：基于连续输注5-氟尿嘧啶联合表柔比星和奥沙利铂的晚期和转移性胃癌的II期临床试验。
2. Phase II study of epirubicin plus oxaliplatin and infusional 5-fluorouracil as first-line combination therapy in patients with metastatic or advanced gastric cancer. [J] . Zhang CX, Huang S, Xu N, Anti-cancer drugs . 2007,第5期

机译：表柔比星联合奥沙利铂和5-氟尿嘧啶输注作为转移性或晚期胃癌患者的一线联合治疗的第二阶段研究。
3. Epirubicin combined with oxaliplatin and 5-day continuous infusion of 5-fluorouracil as a first-line treatment for metastatic gastric cancer: treatment outcomes and analysis of prognostic factors [J] . Zhu Xiaodong, Zhao Xiaoying, Peng Wei, Journal of Cancer Research and Clinical Oncology . 2015,第1期

机译：表柔比星联合奥沙利铂和5天连续输注5-氟尿嘧啶作为转移性胃癌的一线治疗：治疗结果和预后因素分析
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. Clinical predictive value of pre-clinical cancer models: A study of the predictive value of the in vitro cell line, human xenograft and murine allograft pre-clinical cancer models for phase II clinical trials of cytotoxic cancer drugs [D] . Voskoglou-Nomikos, Theodora 2001

机译：临床前癌症模型的临床预测价值：体外细胞系，人异种移植和小鼠同种异体移植临床前癌症模型对细胞毒性癌症药物II期临床试验的预测价值研究
6. Phase II study of continuous infusional 5-fluorouracil with epirubicin and carboplatin (instead of cisplatin) in patients with metastatic/locally advanced breast cancer (infusional ECarboF): a very active and well-tolerated outpatient regimen. [O] . H. Bonnefoi, I. E. Smith, M. E. OBrien, 1996

机译：在转移/局部晚期乳腺癌（输注ECarboF）患者中连续注入5-氟尿嘧啶和表柔比星和卡铂（代替顺铂）的II期研究：一种非常活跃且耐受良好的门诊方案。
7. Phase II study of continuous infusional 5-fluorouracil with epirubicin and carboplatin (instead of cisplatin) in patients with metastatic/locally advanced breast cancer (infusional ECarboF): a very active and well-tolerated outpatient regimen. [O] . Bonnefoi, H., Smith, I. E., O'Brien, M. E., 1996

机译：在转移/局部晚期乳腺癌（输注ECarboF）患者中连续注入5-氟尿嘧啶和表柔比星和卡铂（代替顺铂）的II期研究：一种非常活跃且耐受良好的门诊方案。

Phase II clinical trial of advanced and metastatic gastric cancer based on continuous infusion of 5-fluorouracil combined with epirubicin and oxaliplatin

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