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Malaria in India: Challenges and opportunities

机译:印度的疟疾:挑战与机遇

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India contributes about 70% of malaria in the South East Asian Region of WHO. Although annually India reports about two million cases and 1000 deaths attributable to malaria, there is an increasing trend in the proportion of Plasmodium falciparum as the agent. There exists heterogeneity and variability in the risk of malaria transmission between and within the states of the country as many ecotypes/paradigms of malaria have been recognized. The pattern of clinical presentation of severe malaria has also changed and while multi-organ failure is more frequently observed in falciparum malaria, there are reports of vivax malaria presenting with severe manifestations. The high burden populations are ethnic tribes living in the forested pockets of the states like Orissa, Jharkhand, Madhya Pradesh, Chhattisgarh and the North Eastern states which contribute bulk of morbidity and mortality due to malaria in the country. Drug resistance, insecticide resistance, lack of knowledge of actual disease burden along with new paradigms of malaria pose a challenge for malaria control in the country. Considering the existing gaps in reported and estimated morbidity and mortality, need for estimation of true burden of malaria has been stressed. Administrative, financial, technical and operational challenges faced by the national programme have been elucidated. Approaches and priorities that may be helpful in tackling serious issues confronting malaria programme have been outlined.
机译:印度占世卫组织东南亚区域疟疾的约70%。尽管印度每年报告约200万例疟疾病例和1000例死亡,但恶性疟原虫作为病原体的比例呈上升趋势。由于人们认识到许多生态类型/范例的疟疾,在国家之间和国家内部,疟疾传播的风险存在异质性和变异性。严重疟疾的临床表现方式也已改变,尽管在恶性疟疾中多器官衰竭的发生率更高,但有报道说间日间疟疾有严重表现。高负担人口是生活在奥里萨邦(Orissa),贾坎德邦(Jharkhand),中央邦(Madhya Pradesh),恰蒂斯加尔邦(Chhattisgarh)和东北邦等州森林茂密的地区的族裔部落,这些地区造成了该国因疟疾而发病和死亡的大部分。耐药性,杀虫剂耐药性,对实际疾病负担的缺乏认识以及新的疟疾范式对该国的疟疾控制构成了挑战。考虑到报告和估计的发病率和死亡率方面存在的差距,已经强调需要估计疟疾的真正负担。阐明了国家方案面临的行政,财政,技术和业务挑战。概述了可能有助于解决疟疾规划所面临的严重问题的方法和重点。

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