Bifunctional Activities of Valerophenone Synthase in Hop (Humulus lupulus L.)

摘要

Valerophenone synthase (VPS) catalyzes the biosynthesis of pholoris- ovalerophenone, which is a precursor of hop (Humulus lupulus L.) resin. The VPS gene is specifically expressed in the lupulin gland, and the enzyme Has a high similarity to chalcone synthase (CHS). CHS catalyzes the Formation of naringenin-chalcone; it I considered a precursor of the Prenylflavonoids, which accumulate in the lupulin gland. We tried to Confirm whether VPS has CHS activity using the purified translation Product of the VPS gene expressed in Escherichia coli.