Asymmetric synthesis of tetrahydrofurans by competitive [1,2]-phenylsulfanyl (PhS) migrations under thermodynamic control

摘要

Triols were prepared in enantiomerically enriched form by a short route that included a Sharpless asymmetricndihydroxylation; treatment of these triols with toluene-p-sulfonic acid gave THFs as thermodynamic products.