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Mumps Antibody Levels Among Students Before a Mumps Outbreak: In Search of a Correlate of Immunity

机译:流行性腮腺炎暴发前学生中的流行性腮腺炎抗体水平:寻找相关的免疫力

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Background. In 2006, a mumps outbreak occurred on a university campus despite ≥ 95% coverage of students with 2 doses of measles-mumps-rubella (MMR) vaccine. Using plasma samples from a blood drive held on campus before identification of mumps cases, we compared vaccine-induced preoutbreak mumps antibody levels between individuals who developed mumps (case patients) and those who did not develop mumps (nonpatients).
机译:背景。 2006年,尽管使用2剂麻疹-腮腺炎-风疹(MMR)疫苗的学生覆盖率≥95%,但大学校园内仍出现腮腺炎暴发。在确定流行性腮腺炎病例之前,使用校园内血液驱动器的血浆样本,我们比较了患有流行性腮腺炎的人(病例患者)和未患有流行性腮腺炎的人(非患者)之间疫苗诱导的暴发流行性腮腺炎抗体水平。

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  • 来源
    《Journal of Infectious Diseases》 |2011年第9期|p.1413-1422|共10页
  • 作者单位

    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases;

    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases;

    Community Blood Center of Greater Kansas City, Missouri;

    Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland;

    Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland;

    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases;

    Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia;

    Community Blood Center of Greater Kansas City, Missouri;

    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases;

    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases;

    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases;

    Kansas Department of Health and Environment, Topeka;

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