High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-blind Randomized Placebo Controlled Clinical Trial

Anuradha Ganesan; Nancy Crum-Cianflone; Jeanette Higgins; Jing Qin; Catherine Rehm; Julia Metcalf; Carolyn Brandt; Jean Vita; Catherine F. Decker; Peter Sklar; Mary Bavaro; Sybil Tasker; Dean Follmann

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High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-blind Randomized Placebo Controlled Clinical Trial

机译：大剂量阿托伐他汀可降低免疫激活的细胞标志物，而不会影响HIV-1 RNA水平：双盲随机安慰剂对照临床试验的结果

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(See the editorial commentary by Carr, on pages 751–2.)

机译：（请参阅Carr的社论评论，第751-2页。）

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《Journal of Infectious Diseases》 |2011年第6期|p.756-764|共9页
作者
Anuradha Ganesan; Nancy Crum-Cianflone; Jeanette Higgins; Jing Qin; Catherine Rehm; Julia Metcalf; Carolyn Brandt; Jean Vita; Catherine F. Decker; Peter Sklar; Mary Bavaro; Sybil Tasker; Dean Follmann;
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National Naval Medical Center, Division of Infectious Diseases and|Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, Maryland;

Infectious Disease Clinical Research Program, Uniformed Services University, Bethesda, Maryland|Naval Medical Center San Diego, Division of Infectious Diseases, California;

AIDS Monitoring Laboratory, Clinical Services Program, Science Applications International Corporation–Frederick, Inc, National Cancer Institute-Frederick;

Biostatistics Research Branch;

Clinical Research Section;

Biostatistics Research Branch, Clinical Research Branch, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland;

Naval Medical Center San Diego, Division of Infectious Diseases, California;

National Naval Medical Center, Division of Infectious Diseases and;

National Naval Medical Center, Division of Infectious Diseases and;

Department of Medicine, Drexel University College of Medicine, Philadelphia|Merck Research Laboratories, North Wales, Pennsylvania;

Naval Medical Center San Diego, Division of Infectious Diseases, California;

Pharmaceutical Product Development, Incorporated, Wilmington, Delaware;

Biostatistics Research Branch;

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1. High dose atorvastatin decreases cellular markers of immune activation without affecting HIV-1 RNA levels: results of a double-blind randomized placebo controlled clinical trial. [J] . Ganesan A, Crum Cianflone N, Higgins J, The Journal of Infectious Diseases . 2011,第6期

机译：高剂量阿托伐他汀可降低免疫激活的细胞标志物，而不会影响HIV-1 RNA水平：双盲随机安慰剂对照临床试验的结果。
2. Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial [J] . Jacobson Jeffrey M., Routy Jean-Pierre, Welles Seth, JAIDS: Journal of acquired immune deficiency syndromes . 2016,第1期

机译：使用自体HIV-1 RNA的HIV-1感染的树突状细胞免疫疗法：一项随机，双盲，安慰剂对照的临床试验。
3. Sertraline treatment decreased the serum levels of interleukin-6 and high-sensitivity C-reactive protein in hematopoietic stem cell transplantation patients with depression; a randomized double-blind, placebo-controlled clinical trial [J] . Bone marrow transplantation . 2020,第4期

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5. The effects of isosorbide mononitrate on markers of bone turnover: A double-blind randomized placebo controlled trial. [D] . Jamal, Abida Sophie. 2003

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6. Editors Choice: High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-blind Randomized Placebo Controlled Clinical Trial [O] . Anuradha Ganesan, Nancy Crum-Cianflone, Jeanette Higgins, -1

机译：编辑推荐：大剂量阿托伐他汀在不影响HIV-1 RNA水平的情况下降低免疫激活的细胞标志物：双盲随机安慰剂对照临床试验的结果
7. High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-blind Randomized Placebo Controlled Clinical Trial [O] . Ganesan, Anuradha, Crum-Cianflone, Nancy, Higgins, Jeanette, 2011

机译：大剂量阿托伐他汀可降低免疫激活的细胞标志物，而不会影响HIV-1 RNA水平：双盲随机安慰剂对照临床试验的结果
8. High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-Blind Randomized Placebo Controlled Clinical Trial [R] . Ganesan, A., Crum-Cianflone, N., Higgins, J., 2011

机译：高剂量阿托伐他汀减少免疫激活的细胞标记而不影响HIV-1 RNa水平：双盲随机安慰剂对照临床试验的结果

High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-blind Randomized Placebo Controlled Clinical Trial

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