Real-time blood flow visualization using the graphics processing unit

摘要

Abstract. Laser speckle imaging (LSI) is a technique in which coherent light incident on a surface produces anreflected speckle pattern that is related to the underlying movement of optical scatterers, such as red blood cells,nindicating blood flow. Image-processing algorithms can be applied to produce speckle flow index (SFI) maps ofnrelative blood flow.We present a novel algorithm that employs the NVIDIA Compute Unified Device Architecturen(CUDA) platform to perform laser speckle image processing on the graphics processing unit. Software writtennin C was integrated with CUDA and integrated into a LabVIEW Virtual Instrument (VI) that is interfaced with anmonochrome CCD camera able to acquire high-resolution raw speckle images at nearly 10 fps. With the CUDAncode integrated into the LabVIEW VI, the processing and display of SFI images were performed also at ∼10 fps.nWe present three video examples depicting real-time flow imaging during a reactive hyperemia maneuver, withnfluid flow through an in vitro phantom, and a demonstration of real-time LSI during laser surgery of a port winenstain birthmark. C u00022011 Society of Photo-Optical Instrumentation Engineers (SPIE). [DOI: 10.1117/1.3528610]