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Estimating past inhalation exposure to asbestos: A tool for risk attribution and disease screening

机译:估计过去的石棉吸入暴露:风险归因和疾病筛查的工具

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摘要

Introduction: Late presentation is common in mesothelioma. Reliable assessment of past exposure to asbestos is a necessary first step for risk attribution and for the development of a future screening programme. Such a programme could maximise access to trials of novel therapies and would pave the way for development of novel chemoprophylaxis strategies. This paper describes a method for individual exposure reconstruction along with data from a validation study.
机译:简介:间皮瘤晚期表现很常见。可靠地评估过去接触石棉是风险归因和制定未来筛查计划的必要第一步。这样的程序可以最大程度地获得新疗法的试验机会,并为开发新的化学预防策略铺平道路。本文介绍了一种用于个体暴露重建的方法以及来自验证研究的数据。

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  • 作者单位

    Heriot Watt Univ, Inst Biol Chem Biophys & Bioengn, Edinburgh EH14 4AS, Midlothian, Scotland|Inst Occupat Med, Res Ave North, Edinburgh EH14 4AP, Midlothian, Scotland;

    Inst Occupat Med, Res Ave North, Edinburgh EH14 4AP, Midlothian, Scotland;

    Queen Elizabeth Univ Hosp, Pleural Dis Unt, Glasgow G51 4TF, Lanark, Scotland|Univ Glasgow, Inst Infect Immun & Inflammat, Glasgow G12 8TA, Lanark, Scotland;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Mesothelioma; Screening; Asbestos; Exposure;

    机译:间皮瘤;筛查;石棉;暴露;
  • 入库时间 2022-08-18 03:47:51

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