Subdiffusion in a system consisting of two different media separated by a thin membrane

摘要

We consider subdiffusion in a system which consists of two media separated by a thin membrane. The subdiffusion parameters may be different in each of the medium. Using the new method presented in this paper we derive the probabilities (the Green's functions) describing a particle's random walk in the system. Within this method we firstly consider the particle's random walk in a system with both discrete time and space variables in which a particle can vanish due to reactions with constant probabilities R_1 and R_2 defined separately for each medium. Then, we move from discrete to continuous variables. The reactions included in the model play a supporting role. We link the reaction probabilities with the other subdiffusion parameters which characterize the media by means of the formulae presented in this paper. Calculating the generating functions for the difference equations describing the random walk in the composite membrane system with reactions, which depend explicitly on R_1 and R_2, we are able to correctly incorporate the subdiffusion parameters of both the media into the Green's functions. Finally, placing R_1 = R_2 = 0 into the obtained functions we get the Green's functions for the composite membrane system without any reactions. From the obtained Green's functions, we derive the boundary conditions at the thin membrane. One of the boundary conditions contains the Riemann-Liouville fractional time derivatives, which show that the additional 'memory effect' is created by a discontinuity of the system. The second boundary condition demands continuity of a flux at the membrane. We also derive a new formula describing time evolution of releasing substance from subdiffusive medium. This function coincides well with experimental data presented in Arabski et al. (2009). Confronting the experimental data with the derived formula, we estimate subdiffusive parameters of colistin in gel 1% aqueous agarose solution. We show the subdiffusive character of colistin transport in the gel.