Reanalysis of two studies with contrasting results on the association between statin use and fracture risk: the General Practice Research Database

摘要

Background Two recent case–control studies by Meier et al. and van Staa et al. used the UK General Practice Research Database (GPRD) to examine the association between the use of statins and the risk of fractures, with different results. The objective of the present study was to examine methodological explanations for the discrepant results.