An Insight into Calculus of Communicating System and Formalisms for Bio-inspired Logic Device Design using Computational Aspects of Protocells

摘要

In this paper, we consider bio-inspired logic device modelling based on protocells using process algebra-based Efficient Symbolic Tools package (EST) and analyse a case study through simulation to highlight the importance of bio-inspired computational platforms. As a promising inheritance from systems biology and computational cell biology, synthetic biology uses a wide variety of mathematical descriptions including graph theory, boolean logic, ordinary, partial and stochastic differential equations. It is the solid feedback between an accurate and realistic modelling of the subject under investigation and the precise reproduction of the genetic or chemical design in the laboratory that has recently granted synthetic biology a high-profde attention in the scientific community. We explore here how and why protocells can provide a good basis to model logical components, and how molecular modelling methods allow understanding the physical mechanism of this process.