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Biocompatibility of Biodegradable Polymer Films Based on Poly(lactic-co-glycolic acid) of Various Molecular Weights

机译:基于不同分子量的聚乳酸-乙醇酸共聚物的可生物降解聚合物薄膜的生物相容性

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摘要

Various poly(lactic- co -glycolic acid)-based polymeric films with various molecular weights were obtained. The mechanical characteristics of these films were investigated. It was shown that the obtained polymer films do not have a short-term toxic effect on mammalian cells. The percentage of actively dividing cells on such polymer films is 1.5–3.0 times higher than when grown on culture glass, and, accordingly, the cell layer is formed faster. The obtained poly(lactic- co -glycolic acid)-based polymer films are biocompatible.
机译:获得了具有各种分子量的各种基于聚(乳酸-共-乙醇酸)的聚合物膜。研究了这些膜的机械特性。结果表明,所获得的聚合物膜对哺乳动物细胞没有短期毒性作用。在这种聚合物膜上活跃分裂的细胞百分比是在培养玻璃板上生长时的1.5-3.0倍,因此,细胞层的形成速度更快。所得的基于聚(乳酸-乙醇酸共聚物)的聚合物膜是生物相容的。

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