NattoPharma highlights new evidence connecting statin use to increased cardiovascular risk, illustrating the impact of Vitamin K2 supplementation for statin users

摘要

A NEW CROSS-SECTIONAL clinical study published in Kaohsiung Journal of Medical Sciences adds to the evidence that statins, a heavily prescribed cholesterol medication, may enhance calcium accumulation in the arterial wall by inhibiting vitamin K-dependent proteins involved in vascular protection.Statins are first line drugs in the prevention and treatment of established atherosclerotic cardiovascular disease. Paradoxically, intensive statin therapy has been shown to increase vascular calcification and accelerate its progression. The aim of the recently published study, "Statins, vascular calcification, and vitamin K-dependent proteins: Is there a relation?", was to find a putative relation between statin use, coronary calcification, and the vitamin K-dependent proteins as a possible mechanism mediating statins' pro-calcification.