Shedding Light on Skin Disorders

摘要

Watching microscopic cellular behaviour and simultaneously quantifying sub-cellular changes in protein concentrations will significantly increase basic understanding of biology. A group of Singapore scientists at the Centre for Molecular Medicine (CMM) employs fluorescence time-lapse microscopy to study the dynamics of the keratin intermediate-filament network in human skin cells, comparing the behaviour of wild-type cells to those containing mutant filament proteins associated with genetic skin disorders.