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The Applicability of Epidemiological Methods to the Assessment of the Risks to Human Health of Indoor Air Pollution: An Overview

机译:流行病学方法在室内空气污染对人类健康风险评估中的适用性:概述

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摘要

Western populations spend the vast majority of their time indoors, and can be exposed to a range of indoor pollutants that may have adverse effects on health. Scientists and regulators need to be able to understand and quantify the nature of the potential risks posed by the indoor environment. Epidemiological methods are available to investigate relationships between indoor pollutant exposure and health impacts, but involve many assumptions and have inherent uncertainties. To establish an accurate understanding of the knowledge base and a sound interpretation of the significance of the results obtained, it is essential that epidemiological study findings are not accepted uncritically and that the advantages/weaknesses of each design are fully understood. This overview identifies the strengths and weaknesses of the various epidemiological techniques usedrnto study indoor air pollution, and considers the place of epidemiological data within the wider weight of evidence considerations necessary to establish causality of associations and accurately determine potential risk.rnIt is evident that epidemiology remains a key science in the study of associations between indoor air pollutants and diseases like asthma, and a number of recommendations are made that may improve the application of this methodology and the interpretation of derived results.
机译:西方人将大部分时间都花在室内,并且可能会接触到可能对健康造成不利影响的一系列室内污染物。科学家和监管机构需要能够理解和量化室内环境带来的潜在风险的性质。流行病学方法可用于调查室内污染物暴露与健康影响之间的关系,但涉及许多假设且具有内在的不确定性。为了建立对知识库的准确理解并正确解释获得的结果的重要性,至关重要的是,不要不加批判地接受流行病学研究结果,并且必须充分理解每种设计的优点/缺点。本概述概述了用于研究室内空气污染的各种流行病学技术的优缺点,并考虑了流行病学数据在建立关联因果关系和准确确定潜在风险所必需的更广泛的证据考虑因素中的位置。显然,流行病学仍然存在研究室内空气污染物与哮喘等疾病之间关系的关键科学,并提出了一些建议,可能会改善这种方法的应用以及对衍生结果的解释。

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