Studies on Application of Advanced Oxidation Processes for Degradation of p-Anisaldehyde and Dimethylsulphoxide in Combined Wastewaters From Bulk Drugs Manufacturing Processes

摘要

Recent progress in chemical water treatment has led to the development of advanced oxidation processes (AOPs). AOPs are based on the generation of hydroxyl radicals that can often achieve oxidative destruction of compounds refractory to the conventional ozonation or H_2O_2 oxidation. Therefore, industrial wastewaters from bulk drugs (diltiazem hydrochlo-ride and ketoconazole) manufacturing processes were treated with UV/H_2O_2, UV/Fentons reagent, UV/TiO_2 hetrogenous photo oxidation process as pretreatment step. Experiments were conducted by combining the two wastewater streams of two different bulk drugs manufacturing processes for determining the effectiveness of AOPs suited for the effective degradation of p-anisaldehyde (initial concentrations 22,355 ppm, COO 2,08000 mg/L, BOD 34000 mg/L) and dimethylsulphoxide (initial concentration 27444 ppm, COD 70147 mg/L, BOD 15150 mg/L). A UV/Fenton AOP was found to cost effectively treat the majority of refractory toxic organics with upto 70% COD removal and 89% compound degradation. This UV/Fenton treatment was affected by pH at 3. the UV/Fenton treatment process was compared with the conventional biological treatment process to evaluate the cost effectiveness.