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A combined half-cone beam and parallel hole collimation system for SPECT brain imaging

机译:半锥束和平行孔组合准直系统用于SPECT脑成像

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The authors' research group has recently examined new types of collimator designs with the goal of improving sensitivity and lesion detection for head imaging. One of these collimator designs is a half-cone beam collimator. However, the sensitivity is reduced as objects are removed from the focal line and it does not satisfy Tuy's sufficiency condition. Parallel hole collimation does not have this problem with axial blurring, however, values for sensitivity are not as large as for half-cone collimators. A potential configuration is to use one parallel hole collimator in conjunction with two half-cone beam collimators on a triple camera single photon emission computed tomography (SPECT) system. This might produce results that represent the best of both collimation systems. The authors acquired projection data with a Defrise disk phantom filled with Tc-99m. A half-cone beam collimator with a focal length of 50 cm was placed on one head of a triple camera SPECT system. A low energy super high resolution (LESR) parallel hole collimator was placed on a second head. Different projection data sets were combined to model acquisition in the three headed gamma camera with three half-cone beam collimators, two half-cone beam and one parallel beam collimators, one half-cone beam and two parallel beam collimators and three parallel beam collimators. Image reconstruction used a modified maximum likelihood maximization-expectation (ML-EM) algorithm. For the reconstruction with three half-cone beam collimators, the authors observe axial blurring. This is largely reduced with two half-cone beam and one parallel beam collimators. Graphs of the image profiles demonstrate that the blurring along the axial direction is decreased with the addition of parallel hole collimators.
机译:作者的研究小组最近检查了新型准直仪设计,目的是提高头部成像的灵敏度和病变检测。这些准直仪设计之一是半锥形光束准直仪。但是,随着物体从焦距移开,灵敏度降低,并且不满足Tuy的充分条件。平行孔准直不存在轴向模糊的问题,但是,灵敏度值不如半锥形准直仪大。一种可能的配置是在三重相机单光子发射计算机断层扫描(SPECT)系统上结合使用一个平行孔准直仪和两个半圆锥光束准直仪。这可能会产生代表两种准直系统中最好的结果。作者使用填充有Tc-99m的Defrise盘体模获得了投影数据。将焦距为50 cm的半锥形光束准直仪放在三镜头SPECT系统的一个头上。将低能超高分辨率(LESR)平行孔准直仪放在第二个头上。组合了不同的投影数据集,以在具有三个半圆锥光束准直仪,两个半圆锥光束和一个平行光束准直仪,一个半圆锥光束和两个平行光束准直仪以及三个平行光束准直仪的三头伽马相机中进行模型采集。图像重建使用改进的最大似然最大化期望(ML-EM)算法。对于使用三个半锥形光束准直器进行的重建,作者观察到轴向模糊。使用两个半锥形光束和一个平行光束准直器可以大大减少这种情况。图像轮廓图表明,通过添加平行孔准直器,可以减少沿轴向的模糊。

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