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Home-Based Monitoring and Assessment of Parkinson's Disease

机译:帕金森氏病的家庭监测和评估

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摘要

As a clinically complex neurodegenerative disease, Parkinson''s disease (PD) requires regular assessment and close monitoring. In our current study, we have developed a home-based tool designed to monitor and assess peripheral motor symptoms. An evaluation of the tool was carried out over a period of ten weeks on ten people with idiopathic PD. Participants were asked to use the tool twice daily over four days, once when their medication was working at its best (“on” state) and once when it had worn off (“off” state). Results showed the ability of the data collected to distinguish the “on” and “off” state and also demonstrated statistically significant differences in timed assessments. It is anticipated that this tool could be used in the home environment as an early alert to a change in clinical condition or to monitor the effects of changes in prescribed medications used to manage PD.
机译:作为临床复杂的神经退行性疾病,帕金森氏病(PD)需要定期评估和密切监测。在当前的研究中,我们开发了一种基于家庭的工具,旨在监视和评估周围运动症状。在十周内对十位特发性PD患者进行了该工具的评估。要求参与者在四天内每天两次使用该工具,一次是在药物达到最佳状态时(“开”状态),一次是在药量耗尽(“关”状态)时使用。结果表明,所收集数据具有区分“开”和“关”状态的能力,并且还显示出在定时评估中的统计学显着差异。预计该工具可在家庭环境中用作临床状况变化的早期警报或监视用于管理PD的处方药变化的影响。

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