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A Chip Integrity Monitor for Evaluating Moisture/Ion Ingress in mm-Sized Single-Chip Implants

机译:一种芯片完整性监测器,用于评估MM大小芯片植入物中的水分/离子进入

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For mm-sized implants incorporating silicon integrated circuits, ensuring lifetime operation of the chip within the corrosive environment of the body still remains a critical challenge. For the chip's packaging, various polymeric and thin ceramic coatings have been reported, demonstrating high biocompatibility and barrier properties. Yet, for the evaluation of the packaging and lifetime prediction, the conventional helium leak test method can no longer be applied due to the mm-size of such implants. Alternatively, accelerated soak studies are typically used instead. For such studies, early detection of moisture/ion ingress using an in-situ platform may result in a better prediction of lifetime functionality. In this work, we have developed such a platform on a CMOS chip. Ingress of moisture/ions would result in changes in the resistance of the interlayer dielectrics (ILD) used within the chip and can be tracked using the proposed system, which consists of a sensing array and an on-chip measurement engine. The measurement system uses a novel charge/discharge based time-mode resistance sensor that can be implemented using simple yet highly robust circuitry. The sensor array is implemented together with the measurement engine in a standard 0.18 mu m 6-metal CMOS process. The platform was validated through a series of dry and wet measurements. The system can measure the ILD resistance with values of up to 0.504 peta-ohms, with controllable measurement steps that can be as low as 0.8M Omega. The system works with a supply voltage of 1.8 V, and consumes 4.78 mA. Wet measurements in saline demonstrated the sensitivity of the platform in detecting moisture/ion ingress. Such a platform could be used both in accelerated soak studies and during the implant's life-time for monitoring the integrity of the chip's packaging.
机译:对于包含硅集成电路的MM尺寸植入物,确保芯片的寿命运行在身体的腐蚀环境中仍然是一个关键挑战。对于芯片的包装,已经报道了各种聚合物和薄陶瓷涂层,证明了高生物相容性和屏障性质。然而,为了评估包装和寿命预测,由于这种植入物的mm尺寸,不能再施加传统的氦泄漏试验方法。或者,通常使用加速浸泡研究。对于这种研究,使用原位平台的水分/离子进入的早期检测可能导致更好地预测寿命功能。在这项工作中,我们在CMOS芯片上开发了这样的平台。水分/离子的入口将导致芯片内使用的层间电介质(ILD)的电阻的变化,并且可以使用所提出的系统跟踪,该系统由感测阵列和片上测量发动机组成。测量系统采用新型充电/放电基的时模电阻传感器,其可以使用简单且高强度的电路实现。传感器阵列与标准0.18μm6-金属CMOS工艺中的测量发动机一起实现。该平台通过一系列干燥和湿测量验证。该系统可以测量具有高达0.504 PETA-OHM的值的阻力,可控测量步骤可低至0.8MΩ0。该系统适用于1.8 V的电源电压,消耗4.78 mA。盐水中的湿法测量证明了平台检测水分/离子进入的灵敏度。这种平台可以在加速浸泡研究中和植入物的寿命期间用于监测芯片包装的完整性。

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