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Laser-induced acoustic stresses under submerged biological membranes

机译:淹没生物膜下的激光诱导声应力

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摘要

Er:YAG lasers are being widely studied as candidates for surgical procedures in liquid environments, such as in ophthalmology. However, while the Er:YAG laser can be a precise and efficient light scalpel, this surgical method includes accompanying stress waves that must be quantified and evaluated for potential harm. In this study, Er:YAG laser-induced stress waves for free running laser pulses were measured over various consecutive treatment periods. Using a spot-poled PVDF hydrophone, measurements were acquired beneath a biological membrane submerged in a saline bath. Results yielded pressures peaks of 300-600 mbar beneath the uncut membrane, which could be harmful for the optic nerve if located directly below the treatment area. Acoustic waves representative of direct laser-liquid interactions were observed immediately following membrane rupture, and yielded much larger pressures. The morphological changes in the acoustic wave can be used as a feedback signal to indicate when the membrane has been cut.
机译:Er:YAG激光器已被广泛研究用作液体环境(例如眼科)中的外科手术的候选方法。然而,尽管Er:YAG激光可以是一种精确而高效的手术刀,但这种外科手术方法包括伴随的应力波,必须对应力波进行量化和评估,以防潜在危害。在这项研究中,在连续的各个治疗周期中测量了Er:YAG激光诱导的自由运行激光脉冲的应力波。使用点极化PVDF水听器,在浸没在盐水浴中的生物膜下进行测量。结果在未切割的膜下方产生300-600 mbar的压力峰值,如果直接位于治疗区域下方,则可能对视神经有害。膜破裂后立即观察到代表直接激光-液体相互作用的声波,并产生更大的压力。声波中的形态变化可以用作反馈信号,以指示何时切割了膜。

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