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Telbivudine in combination with adefovir versus adefovir monotherapy in HBeAg-positive, lamivudine-resistant chronic hepatitis B

机译:替比夫定联合阿德福韦与阿德福韦单药治疗HBeAg阳性,拉米夫定耐药的慢性乙型肝炎

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摘要

Lamivudine (LAM) resistance is common on lamivudine monotherapy for chronic hepatitis B. This study examined the safety and efficacy of telbivudine (LDT) given with adefovir (ADV) versus ADV monotherapy in patients with chronic, lamivudine-resistant HBV infection.
机译:拉米夫定单药治疗慢性乙型肝炎对拉米夫定(LAM)耐药是常见的。这项研究检查了阿德福韦(ADV)相对于ADV单药治疗的替比夫定(LDT)与慢性拉米夫定耐药性HBV感染患者的安全性和有效性。

著录项

  • 来源
    《Hepatology International》 |2012年第4期|p.696-706|共11页
  • 作者单位

    Department of Internal Medicine, Yonsei University College of Medicine, 250 Seongsanno, Seoul, South Korea;

    The Kyungpook National University Hospital, Daegu, Korea;

    Department of Medicine/Gastroenterology, Samsung Medical Centre, Seoul, Korea;

    Division of Gastroenterology, Hanyang University Guri Hospital, Gyeonggi-do, Suwon, Korea;

    Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea;

    Hallym University Sacred Heart Hospital, Chuncheon, Korea;

    NKC Institute of Gastroenterology and Hepatology, Songklanagarind Hospital, Prince of Songkla University, Hat Yai, Thailand;

    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, Hong Kong;

    Phramongkutklao Hospital, Bangkok, Thailand;

    Tri-Service General Hospital, Taipei, Taiwan, R.O.C;

    Novartis Pharma AG, Basel, Switzerland;

    Novartis Pharma AG, Basel, Switzerland;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Telbivudine; Adefovir; Lamivudine-resistant; Hepatitis B;

    机译:替比夫定;阿德福韦;拉米夫定耐药;乙型肝炎;

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