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Clinical value of multidetector CT coronary angiography as a preoperative screening test before non-coronary cardiac surgery

机译:多层螺旋CT冠状动脉造影作为非冠状动脉心脏手术前术前筛查试验的临床价值

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Objective: Myocardial scintigraphy and/or conventional angiography (CA) are often performed before cardiac surgery in an attempt to identify unsuspected coronary artery disease which might result in significant cardiac morbidity and mortality. Multidetector CT coronary angiography (MDCTCA) has a recognised high negative predictive value and may provide a non-invasive alternative in this subset of patients. The aim of this study was to evaluate the clinical value of MDCTCA as a preoperative screening test in candidates for non-coronary cardiac surgery. Methods: 132 patients underwent MDCTCA (Somatom Sensation 16 Cardiac, Siemens) in the assessment of the cardiac risk profile before surgery. Coronary arteries were screened for ≥ 50% stenosis. Patients without significant stenosis (Group 1) underwent surgery without any adjunctive screening tests while all patients with coronary lesions 3=50% at MDCTCA (Group 2) underwent CA. Results: 16 patients (12.1%) were excluded due to poor image quality. 71 patients without significant coronary stenosis at MDCTCA were submitted to surgery. 30 out of 36 patients with significant (≥ 50%) coronary stenosis at MDCTCA and CA underwent adjunctive bypass surgery or coronary angioplasty. In 8 patients, MDCTCA overestimated the severity of the coronary lesions (> 50% MDCTCA, < 50% CA). No severe cardiovascular perioperative events such as myocardial ischaemia, myocardial infarction or cardiac failure occurred in any patient in Group 1. Conclusions: MDCTCA seems to be effective as a preoperative screening test prior to non-coronary cardiac surgery. In this era of cost containment and optimal care of patients, MDCTCA is able to provide coronary vessel and ventricular function evaluation and may become the method of choice for the assessment of a cardiovascular risk profile prior to major surgery.
机译:目的:经常在心脏手术前进行心肌闪烁显像和/或常规血管造影(CA)检查,以发现可能导致严重心脏发病和死亡的未怀疑的冠状动脉疾病。多层螺旋CT冠状动脉造影(MDCTCA)具有公认的高阴性预测价值,并且可以为该患者亚组提供非侵入性替代方法。这项研究的目的是评估MDCTCA作为非冠状动脉心脏手术候选人的术前筛查测试的临床价值。方法:132例患者接受了MDCTCA(Somatom Sensation 16 Cardiac,Siemens)的手术前心脏风险评估。筛查冠状动脉狭窄≥50%。没有严重狭窄的患者(第1组)未经任何辅助筛查测试而接受手术,而所有在MDCTCA中3%= 50%的冠状动脉病变的患者(第2组)都接受了CA。结果:由于图像质量差,排除了16例患者(12.1%)。在MDCTCA处无明显冠状动脉狭窄的71例患者接受了手术。在MDCTCA和CA发生36例(≥50%)冠状动脉狭窄的患者中,有30例接受了辅助旁路手术或冠状动脉成形术。在8例患者中,MDCTCA高估了冠状动脉病变的严重程度(MDCTCA≥50%,CA≤50%)。第1组的任何患者均未发生严重的心血管围手术期事件,例如心肌缺血,心肌梗塞或心力衰竭。结论:MDCTCA似乎可作为非冠状动脉心脏手术前的术前筛查测试有效。在这个成本控制和患者最佳护理时代,MDCTCA能够提供冠状动脉和心室功能评估,并可能成为在进行大手术之前评估心血管风险的首选方法。

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