Association of angiotensin converting enzyme and angiotensin II type 1 receptor genotypes with left ventricular function and mass in patients with angiographically normal coronary arteries

摘要

Conclusions-These data do not support an association of the ACE and ATlR genotypes on left ventricular hypertrophy in white patients with normal coronary arteries. Objective-To analyse the potential asso- Ciation of the angiotensin converting Enzyme (ACE) and angiotensin II type 1 Receptor (AT1R) gene polymorphisms on Left ventricular function and mass in Patients with normal coronary arteries. Design-Consecutive sample. Setting-University hospital. Subjects-141 consecutive white patients Referred for coronary angiography and With angiographically normal coronary Arteries. Patients with valvar diseases, Cardiomyopathies, or a history of myo- Cardial infarction were excluded.