Prognostic significance of electrical alternans versus signal averaged electrocardiography in predicting the outcome f electrophysiological testing and arrhythmia-free survival

摘要

Objective-To investigate the accuracy of signal averaged electrocardiography (SAECG) and measurement of microvolt level T wave alterans as predictors of susceptibility to ventricular arrhythmias. Design-Analysis of new data from a pre- Viously published prospective investiga- Tion. Conclusions-T wave alternans was a Highly significant predictor of the out- Come of electrophysiological testing and Arrhythmia-free survival, while SAECG Was not a statistically significant predic- Tor. Although these results need to be con- Firmed in prospective clinical studies, they Suggest that T wave alternans may serve As a non-invasive probe for screening high Risk populations for malignant ventricular Arrhythmias.