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首页> 外文期刊>Heart and Vessels >Risk factors for acute shunt blockage in children after modified Blalock-Taussig shunt operations
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Risk factors for acute shunt blockage in children after modified Blalock-Taussig shunt operations

机译:改良的Blalock-Taussig分流手术后儿童急性分流阻塞的危险因素

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Factors relating to acute blockage of modified Blalock-Taussig shunts (MBTS) have not been well described in the literature. Our aim was to determine the outcomes in patients early after undergoing MBTS operations and to identify potential risk factors for acute shunt blockage in the early postoperative period. A retrospective study was performed in a tertiary referral congenital cardiac unit. All children who underwent first shunt insertion for cyanotic congenital heart disease during the study period from 2002 to 2006 were included. Seventy-six children underwent first shunt insertion with a median age of 37 days (range 2 days-8 years) and median weight of 3.75 kg (range 2.1–17.2 kg). The shunt sizes varied from 3 to 6 mm. The rate of acute shunt blockage was 11.8% (9/76), all within the first 24 h. There were 3 early deaths (3.9%), none of which were associated with shunt blockage. The main risk factors for blockage were preoperative high hemoglobin, weight less than 3 kg, and duct patency on echocardiogram after surgery. This study identifies that high preoperative hemoglobin, a weight less than 3 kg at operation, and the presence of a patent duct are statistically significant risk factors for shunt blockage in the acute postoperative period. Further work is needed to determine if reduction in preoperative hemoglobin concentration and attempts to reduce postoperative ductal patency may alter the outcome.
机译:有关改良的Blalock-Taussig分流器(MBTS)的急性阻塞的因素尚未在文献中得到很好的描述。我们的目的是确定接受MBTS手术后患者的结局,并确定术后早期分流阻塞的潜在危险因素。回顾性研究在三级转诊先天性心脏单元中进行。纳入了2002年至2006年研究期间因发first性先天性心脏病而首次分流手术的所有儿童。七十六名儿童进行了首次分流术,中位年龄为37天(范围为2天至8岁),中位体重为3.75千克(范围为2.1-17.2千克)。分流器的大小从3到6 mm不等。急性分流阻塞的发生率为11.8%(9/76),全部发生在开始的24小时内。有3例早期死亡(3.9%),均与分流阻塞无关。阻塞的主要危险因素是术前高血红蛋白,体重少于3 kg和术后超声心动图导管通畅。这项研究表明,术前血红蛋白高,手术时体重小于3千克以及导管未闭是急性术后分流阻塞的统计学显着危险因素。需要做进一步的工作来确定术前血红蛋白浓度的降低和降低术后导管通畅性的尝试是否可能改变预后。

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