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首页> 外文期刊>Graefe's Archive for Clinical and Experimental Ophthalmology >Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells
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Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells

机译:视网膜色素上皮细胞中氧化应激诱导的内质网应激

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摘要

Induction of glucose-regulated protein (GRP)-78 in the endoplasmic reticulum (ER) is a protective mechanism cells use to adapt to ER stress. We evaluated the expression of GRP-78 and its regulation by an oxidant tert-butyl hydroperoxide (tBH) in human retinal pigment epithelium (RPE) cells.
机译:内质网(ER)中葡萄糖调节蛋白(GRP)-78的诱导是细胞用于适应ER应激的保护机制。我们评估了人类视网膜色素上皮细胞(RPE)中GRP-78的表达及其通过氧化剂叔丁基过氧化氢(tBH)的调控。

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  • 作者单位

    Department of Pathology Keck School of Medicine of the University of Southern California 2011 Zonal Ave. HMR 209 Los Angeles CA 90033 USA;

    Department of Pathology Keck School of Medicine of the University of Southern California 2011 Zonal Ave. HMR 209 Los Angeles CA 90033 USA;

    Department of Ophthalmology Keck School of Medicine of the University of Southern California 2011 Zonal Ave. HMR 209 Los Angeles CA 90033 USA;

    Doheny Eye Institute Los Angeles CA 90033 USA;

    Department of Ophthalmology Keck School of Medicine of the University of Southern California 2011 Zonal Ave. HMR 209 Los Angeles CA 90033 USA;

    Department of Pathology Keck School of Medicine of the University of Southern California 2011 Zonal Ave. HMR 209 Los Angeles CA 90033 USA;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    RPE; ER stress; Oxidative stress; GRP-78;

    机译:RPE;ER应激;氧化应激;GRP-78;

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