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首页> 外文期刊>Fresenius Environmental Bulletin >THE TOXICITY OF SELECTED SUNSCREENS TO BRACHIONUS CALYCIFLORUS
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THE TOXICITY OF SELECTED SUNSCREENS TO BRACHIONUS CALYCIFLORUS

机译:精选的防晒霜对花椰菜臂章鱼的毒性

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In this study the toxicity of selected sunscreens belonging to two chemical groups: i.e. derivatives of cinnamic acid and of benzoic acid was assessed. The compounds are found in suncare products (creams, balms and lotions) and in other cosmetics (antiwrinkle creams or lipsticks). Two of them (octyl methoxycinnamate and octyl (dimethylamino)-benzoate) are approved for use as ingredients of cosmetic products in the European Union countries. The Rotoxkit F Chronic bioassay was used to evaluate the toxicity of seven compounds, the organisms (the rotifer Brachionus calyciflorus) being hatched from dormant eggs purchased from MicroBioTests?, (Belgium). Two of the study compounds octyl methoxycinnamate and octyl (dimethylamino)benzoate proved to be the most toxic to rotifers. The toxicity correlated highly with the aliphatic chain structure and lipophilic properties of the compounds as the substances with the highest log P value and a high affinity for lipids, i.e. octyl methoxycinnamate and octyl (dimethylamino)benzoate, demonstrated the highest toxicity.
机译:在这项研究中,评估了属于两个化学组的选定防晒剂的毒性:即肉桂酸和苯甲酸的衍生物。该化合物存在于防晒产品(乳霜,香脂和乳液)和其他化妆品(抗皱霜或口红)中。其中两种(甲氧基肉桂酸辛酯和(二甲基氨基)苯甲酸辛酯)已被批准在欧盟国家中用作化妆品成分。 Rotoxkit F慢性生物测定法用于评估7种化合物的毒性,这些生物(轮虫Brachionus calyciflorus)是从从MicroBioTests?(比利时)购买的休眠卵中孵化而来的。研究中的两种化合物甲氧基肉桂酸辛酯和(二甲基氨基)苯甲酸辛酯被证明对轮虫最具毒性。毒性与化合物的脂族链结构和亲脂性高度相关,因为这些化合物具有最高log P值和对脂质的高亲和力,即甲氧基肉桂酸辛酯和(二甲基氨基)苯甲酸辛酯,显示出最高的毒性。

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