Specific patient-reported outcome measures for Parkinson’s disease: analysis and applications

摘要

Patient-reported outcomes (PROs) are defined as the “patient’s report of a health conditionnand its treatment”. This type of assessment encompasses symptoms, functional status,npsychological well-being, health-related quality of life (HRQoL) and other aspects. PROs arenincreasingly used in clinical practice and research, owing to the uniqueness of the data theynfurnish. The methodology used to design and test PRO instruments is drawn from psychology,nsocial sciences and education. The present review focuses on PROs (since 2000) and HRQoLninstruments specific to Parkinson’s disease. Parkinson’s disease is a complex disease that causesnmotor and nonmotor manifestations, many of which can only be assessed through PROnmeasures. New PRO instruments and active research to improve their scientific quality are tonbe expected in the next 5 years.