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Five-year outcome of stand-alone fusion using carbon cages in cervical disc arthrosis

机译:使用碳笼的独立融合治疗颈椎间盘突出症的五年结果

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From January 1, 2001 to December 31, 2003, in the Neurosurgery Department of Rome University o “Sapienza,” 167 patients underwent anterior surgery for cervical spondylodiscoarthrosis. The levels treated by the anterior stand-alone technique were: C3–C4 (11%), C4–C5 (19%), C5–C6 (40%), and C6–C7 (30%). All patients underwent left anterior presternocleidomastoid–precarotid approach, microdiscectomy, and interbody fusion using a carbon fiber cage filled with hydroxyapatite. All patients were discharged within 48 h after surgery with cervical orthosis. In one case, a hematoma of the surgical site occurred within 12 h of surgery; for this reason the patient underwent surgical revision and was discharged 4 days later. All patients have worn cervical orthosis for a mean period of 7 weeks and underwent radiological follow-up with cervical RX at 1 and 3 months after surgery. All patients underwent follow-up from 54 to 90 months after surgery, and all of them underwent cervical RX, cervical CT scans for the estimate of fusion, and evaluation of neurological status using VAS and NDI. Of 167 patients, 132 were cooperative for this study, 18 were non-cooperative, and 17 died. The estimation of fusion made by cervical CT scans with sagittal reconstruction showed complete osteointegration of the cage in 115 patients (87.1%), while it showed pseudoarthrosis in 17 patients (12.9%). In 24 patients, we observed adjacent segment degeneration, and 13 of these underwent new surgical procedures in this institute or in another hospital. Clinical evaluation with VAS and NDI showed a good outcome, with poorest benefit in patients over 60 years. The clinical analysis showed a good fusion rate in according with literature, 13% of non-fusion rate without clinical evidence and 20% of ASDegeneration but only 10% had required new surgery. We also observed that patients over 60 years of age had less satisfactory outcome, probably related with the evolution of pathophysiological degeneration of the cervical spine. In the opinion, pseudoarthrosis is caused by malpositioning of the carbon fiber cage.
机译:从2001年1月1日至2003年12月31日,在罗马大学神经外科处的“ Sapienza”,有167例因颈椎病,腰椎间盘突出症而接受了前路手术。前路独立技术治疗的水平为:C3-C4(11%),C4-C5(19%),C5-C6(40%)和C6-C7(30%)。所有患者均使用填充有羟基磷灰石的碳纤维笼进行左前胸锁乳突肌-前颈动脉入路,显微椎间盘切除术和椎间融合术。颈椎矫形器术后48小时内所有患者出院。在一种情况下,手术部位的血肿在手术后12小时内发生。因此,患者接受了外科手术翻修,并于4天后出院。所有患者均经历了平均7周的颈椎矫形器手术,并在术后1个月和3个月接受了RX颈椎放射检查。所有患者均在术后54个月至90个月内接受随访,所有患者均接受颈椎RX,颈椎CT扫描以评估融合情况,并使用VAS和NDI评估神经系统状况。在167例患者中,有132例为合作研究,18例为不合作,死亡17例。颈椎CT扫描与矢状面重建术融合的评估显示,有115例患者(87.1%)的笼子完全骨整合,而有17例患者(12.9%)的假性关节炎。在24例患者中,我们观察到相邻节段变性,其中13例在该机构或另一家医院接受了新的手术程序。使用VAS和NDI进行的临床评估显示出良好的效果,而60多年来对患者的益处最差。根据文献分析,临床分析显示良好的融合率,无临床证据的非融合率为13%,ASDegeneration为20%,但仅10%需要进行新手术。我们还观察到60岁以上的患者的预后较差,可能与颈椎病理生理退行性变有关。认为假性关节炎是由碳纤维笼子位置不当引起的。

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