Emotional stress and orthodontic tooth movement: effects on apical root resorption, tooth movement, and dental tissue expressionn of interleukin-1 alpha and calcitonin gene-related peptide immunoreactive nerve fibres in rats

摘要

The aim of the study was to investigate the effect of emotional stress on apical root resorption (ARR) and tooth displacement during orthodontic tooth movement in rats. A further area of interest was to evaluate if the expression of interleukin-1 alpha (IL-1α) as well as the density and distribution of peptidergic nerve fibres immunoreactive to calcitonin gene-related peptide (CGRP) in the periodontal ligament (PDL) are associated with possible stress-induced changes in root resorption and tooth movement.