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Gender-associated differences in pharmacokinetics and anti-arrhythmic effects of flecainide in Japanese patients with supraventricular tachyarrhythmia

机译:氟卡尼特在日本室上性快速性心律失常患者中的药代动力学和抗心律失常作用的性别相关差异

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摘要

We examined the effect of gender-associated differences in pharmacokinetics on the anti-arrhythmic effects of flecainide in Japanese patients with supraventricular tachyarrhythmia and in healthy subjects.
机译:我们研究了药代动力学中性别相关差异对氟卡尼抗在日本室上性快速性心律失常患者和健康受试者中抗心律失常作用的影响。

著录项

  • 来源
    《European Journal of Clinical Pharmacology》 |2007年第10期|951-957|共7页
  • 作者单位

    Department of Pharmaceutical Sciences Graduate School of Comprehensive Human Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki 305-8575 Japan;

    Department of Pharmaceutical Sciences Graduate School of Comprehensive Human Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki 305-8575 Japan;

    Department of Internal Medicine Graduate School of Comprehensive Human Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki 305-8575 Japan;

    Department of Internal Medicine Graduate School of Comprehensive Human Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki 305-8575 Japan;

    Department of Internal Medicine Graduate School of Comprehensive Human Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki 305-8575 Japan;

    Department of Internal Medicine Graduate School of Comprehensive Human Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki 305-8575 Japan;

    Department of Pharmaceutical Sciences Graduate School of Comprehensive Human Sciences University of Tsukuba Ten-nodai 1-1-1 Tsukuba Ibaraki 305-8575 Japan;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Flecainide; Gender-associated difference; Pharmacokinetics; Anti-arrhythmic efficacy; CYP2D6;

    机译:氟卡尼特;性别相关差异;药代动力学;抗心律不齐药;CYP2D6;

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