首页> 外文期刊>European Archives of Oto-Rhino-Laryngology >One stage multilevel surgery (uvulopalatopharyngoplasty, hyoid suspension, radiofrequent ablation of the tongue base with/without genioglossus advancement), in obstructive sleep apnea syndrome
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One stage multilevel surgery (uvulopalatopharyngoplasty, hyoid suspension, radiofrequent ablation of the tongue base with/without genioglossus advancement), in obstructive sleep apnea syndrome

机译:阻塞性睡眠呼吸暂停综合症的一期多级手术(睑盲囊成形术,舌骨悬吊,舌根射频消融伴/不伴舌肌进展)

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摘要

We evaluated the surgical results of a one tempo multilevel surgical approach of the upper airway to treat patients with obstructive sleep apnea syndrome (OSAS) in a prospective case series. Twenty-two patients with OSAS and obstruction at both palatinal and tongue base level, as assessed by sleep endoscopy, underwent UPPP, RFTB, HS with or without GA in one operative session. The mean apnea hypopnea index (AHI) decreased from 48.7 (range 17.4–100.9) to 28.8 (P < 0.0001). The success rate (AHI <20 and >50% reduction in AHI) was 45%, the response rate (reduction in AHI of 20–50%) was 27%. The overall response rate was 72%. The success rates of patients with an AHI <55 and >55 were 56 and 0%, respectively. The overall response rate of patients with an AHI <55 was 78% and >55 was 50%. Improvement of desaturation index was significant from 31.9 to 17.6 (P < 0.0001). Visual analogue scales for snoring and hypersomnolence and the Epworth Sleepiness Scores showed significant improvements too (all P < 0.0001). There was no difference in objective and subjective outcomes between the group with and without GA. This study demonstrates that one stage multilevel surgery, in which genioglossus advancement is not of additional value, is a valuable addition to the therapeutic armentarium and can be considered a viable alternative, objective as well as subjective, to NCPAP or as primary treatment in well selected patients with moderate to severe OSAS with an AHI <55.
机译:我们评估了一种前瞻性多级上呼吸道多级手术方法在阻塞性睡眠呼吸暂停综合症(OSAS)中的治疗效果。通过睡眠内窥镜检查评估的22例OSAS伴有pa骨和舌根阻塞的OSAS患者,在一项手术中接受了UPPP,RFTB,HS合并或不合并GA。平均呼吸暂停低通气指数(AHI)从48.7(范围17.4-100.9)降低到28.8(P <0.0001)。成功率(AHI <20,AHI降低> 50%)为45%,响应率(AHI降低20–50%)为27%。总体回应率为72%。 AHI <55和> 55的患者成功率分别为56%和0%。 AHI <55的患者的总缓解率为78%,> 55的患者为50%。脱饱和指数从31.9显着提高到17.6(P <0.0001)。打analogue和过睡的视觉模拟量表以及Epworth嗜睡分数也显示出显着改善(所有P <0.0001)。有和没有GA的组在客观和主观结果上没有差异。这项研究表明,one舌肌的进展没有附加价值的多阶段分期手术是治疗性天文馆的宝贵补充,可以认为是对NCPAP或主观治疗的可行替代,客观和主观选择OHI <55的中重度OSAS患者。

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  • 来源
    《European Archives of Oto-Rhino-Laryngology》 |2007年第4期|439-444|共6页
  • 作者单位

    Department of Otolaryngology Head and Neck Surgery St Lucas Andreas Hospital Amsterdam The Netherlands;

    Department of Otolaryngology Head and Neck Surgery St Lucas Andreas Hospital Amsterdam The Netherlands;

    Department of Otolaryngology Head and Neck Surgery St Lucas Andreas Hospital Amsterdam The Netherlands;

    Department of Biostatistics St Lucas Andreas Hospital Amsterdam The Netherlands;

    Department of Otolaryngology Head and Neck Surgery St Lucas Andreas Hospital Amsterdam The Netherlands;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Multilevel surgery; Sleep apnea syndrome; CPAP-therapy;

    机译:多层次手术;睡眠呼吸暂停综合征;CPAP疗法;

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