Agile Green Process Design for the Intensified Kolbe-Schmitt Synthesis by Acwmpanying (Simplified) Life Cycle Assessment

摘要

In order to investigate the potential for processrnintensification, various reaction conditions were applied to thernKolbe-Schmitt synthesis starting from resorcinol Different CO_2rnprecursors such as aqueous potassium hydrogencarbonate,rnhydrogencarbonate-based ionic liquids, DiMCARB, or sc-CO_2rnthe application of microwave irradiation for fast volumetricrnheating of the reaction mixture, and die effect of harsh reactionrnconditions were investigated The experiments, carried out inrnconventional batch-wise as well as in continuously operatedrnmicrostructured reactors, aimed at the development of anrnenvironmentally benign process for the preparation of 2,4-rndihydroxybenzoic acid. To provide decision support toward arngreen process design, a research-accompanying simplified liferncycle assessment (SLCA) was performed throughout the whole investigation. Following this approach, it was found thatrnconvective heating methods such as oil bath or electrical heating were more beneficial than the application of microwavernirradiation. Furthermore, the consideration of workup procedures was crucial for a holistic view on die environmental burdens.