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Coal mine fire effects on carcinogenicity and non-carcinogenicity human health risks

机译:煤矿火灾对致癌性和非致癌性对人类健康的影响

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Atmospheric particulate matter (PM) pollution levels and human health risks resulting from exposure to non-anthropogenic pollution sources, such as coal mine-fires, are serious global issues. The toxicity of PM10-bound metals and polycyclic aromatic hydrocarbons (PAHs) was assessed according to their non cancer and cancer risks (CRs) at the mine-fire and in an adjacent city area. Health risks were estimated for inhalation, ingestion, and dermal absorption pathways. The non-cancer risks, presented in terms of the hazard index (HI) and hazard quotient (HQ), were found to be significant (>1) at all locations, except in the mining (for HQ-dermal) and city background area (for HQ-ingestion and HQ-dermal) in children and adults, respectively. The total CR was estimated to be highest at the city nearby the mine fire area (3.31E-02 and 1.93E-02) followed by the mine-fire area (2.66E-02 and 1.71E-02) for children and adults, respectively. The total CR and CR via individual exposure routes were estimated to be in the high risk (10(-3) <= CR < 10(-1)) category at the mine-fire site and adjacent city area. For all exposures, CR levels were calculated to be higher than the acceptable range (from 1.00E-06 to 1.00E-04), except for the CR-inhalation level at the A5 location. Among all elements, Cd and BaPequ were more significant for the CR at the coal mine-fire and the adjacent city area. Hence, this study concluded that non-anthropogenic sources, such as coal mine-fires, could be part for the significant health risk (carcinogenic and non carcinogenic) levels in the study area. (C) 2019 Elsevier Ltd. All rights reserved.
机译:由于暴露于非人为污染源(例如煤矿火灾)而导致的大气颗粒物(PM)污染水平和人类健康风险是严重的全球性问题。根据与PM10结合的金属和多环芳烃(PAH)的非致癌性以及在矿井火灾和邻近城市地区的致癌风险(CR),评估了其毒性。估计吸入,摄入和皮肤吸收途径的健康风险。发现在所有位置(在采矿(对于HQ-真皮)和城市背景区域除外)中,以危险指数(HI)和危险商(HQ)表示的非癌症风险是显着的(> 1)。 (用于HQ摄入和HQ-真皮)分别用于儿童和成人。据估计,儿童和成人的雷区附近的城市的总CR最高(3.31E-02和1.93E-02),其次是儿童和成人的雷区(2.66E-02和1.71E-02),分别。在矿井火灾现场和邻近城市地区,通过个体暴露途径的总CR和CR估计为高风险(10(-3)<= CR <10(-1))类。对于所有暴露,除A5位置的CR吸入水平外,CR水平均被计算为高于可接受范围(从1.00E-06至1.00E-04)。在所有元素中,Cd和BaPequ对煤矿火灾和邻近城市地区的CR的影响更大。因此,这项研究得出的结论是,非人为来源,例如煤矿大火,可能是造成研究区域重大健康风险(致癌和非致癌)水平的一部分。 (C)2019 Elsevier Ltd.保留所有权利。

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