CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment

Llop Sabrina; Tran Van; Ballester Ferran; Barbone Fabio; Sofianou-Katsoulis Aikaterini; Sunyer Jordi; Engstrom Karin; Alhamdowk Ayman; Love Tanzy M.; Watson Gene E.; Bustamante Mariona; Murcia Mario; Iniguez Carmen; Shamlaye Conrad F.; Rosolen Valentina; Mariuz Marika; Horvat Milena; Tratnik Janja S.; Mazejn Darja; van Wijngaarden Edwin; Davidson Philip W.; Myers Gary J.; Rand Matthew D.; Broberg Karin

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CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment

机译：CYP3A基因与产前甲基汞暴露与神经发育的关系

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Background: Results on the association between prenatal exposure to methylmercury (MeHg) and child neuropsychological development are heterogeneous. Underlying genetic differences across study populations could contribute to this varied response to MeHg. Studies in Drosophila have identified the cytochrome p450 3A (CYP3A) family as candidate MeHg susceptibility genes.

机译：背景：产前甲基汞（MeHg）暴露与儿童神经心理发育之间的关联性研究结果不一。研究人群之间潜在的遗传差异可能导致对MeHg的这种不同反应。果蝇的研究已确定细胞色素p450 3A（CYP3A）家族为候选MeHg易感基因。

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来源
《Environment international》 |2017年第8期|34-42|共9页
作者
Llop Sabrina; Tran Van; Ballester Ferran; Barbone Fabio; Sofianou-Katsoulis Aikaterini; Sunyer Jordi; Engstrom Karin; Alhamdowk Ayman; Love Tanzy M.; Watson Gene E.; Bustamante Mariona; Murcia Mario; Iniguez Carmen; Shamlaye Conrad F.; Rosolen Valentina; Mariuz Marika; Horvat Milena; Tratnik Janja S.; Mazejn Darja; van Wijngaarden Edwin; Davidson Philip W.; Myers Gary J.; Rand Matthew D.; Broberg Karin;
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作者单位

Univ Valencia, FISABIO Univ Jaume 1, Epidemiol & Environm Hlth Joint Res Unit, Av Catalunya 21, Valencia 46020, Spain|Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Av Monforte Lemos,3-5 Pabellon 11, Madrid 28029, Spain;

Univ Rochester, Med Ctr, Sch Med & Dent, 601 Elmwood Ave,Box 671, Rochester, NY 14642 USA;

Univ Valencia, FISABIO Univ Jaume 1, Epidemiol & Environm Hlth Joint Res Unit, Av Catalunya 21, Valencia 46020, Spain|Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Av Monforte Lemos,3-5 Pabellon 11, Madrid 28029, Spain;

Univ Udine, Dept Med & Biol Sci, Via Colugna 50, I-33100 Udine, Italy|Inst Maternal & Child Hlth IRCCS Burlo Garofolo, Via Istria 65-1, I-34137 Trieste, Italy;

Inst Child Hlth, Dept Social & Dev Paediat, Athens, Greece;

Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Av Monforte Lemos,3-5 Pabellon 11, Madrid 28029, Spain|Ctr Res Environm Epidemiol CREAL, ISGlobal, Av Aiguader 88, Barcelona 08003, Spain|Hosp del Mar, Med Res Inst, IMIM, Av Aiguader 88, Barcelona 08003, Spain|UPF, Av Aiguader 88, Barcelona 08003, Spain;

Lund Univ, Div Occupat & Environm Med, S-22185 Lund, Sweden;

Karolinska Inst, Inst Environm Med, Nobels Vag 13, S-17177 Stockholm, Sweden;

Univ Rochester, Med Ctr, Sch Med & Dent, 601 Elmwood Ave,Box 671, Rochester, NY 14642 USA;

Univ Rochester, Med Ctr, Sch Med & Dent, 601 Elmwood Ave,Box 671, Rochester, NY 14642 USA;

Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Av Monforte Lemos,3-5 Pabellon 11, Madrid 28029, Spain|Ctr Res Environm Epidemiol CREAL, ISGlobal, Av Aiguader 88, Barcelona 08003, Spain|Hosp del Mar, Med Res Inst, IMIM, Av Aiguader 88, Barcelona 08003, Spain|Ctr Genom Regulat CRG, Bioinformat & Genom Program, Genom & Dis Grp, Av Aiguader 88, Barcelona 08003, Spain;

Univ Valencia, FISABIO Univ Jaume 1, Epidemiol & Environm Hlth Joint Res Unit, Av Catalunya 21, Valencia 46020, Spain|Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Av Monforte Lemos,3-5 Pabellon 11, Madrid 28029, Spain;

Univ Valencia, FISABIO Univ Jaume 1, Epidemiol & Environm Hlth Joint Res Unit, Av Catalunya 21, Valencia 46020, Spain|Spanish Consortium Res Epidemiol & Publ Hlth CIBE, Av Monforte Lemos,3-5 Pabellon 11, Madrid 28029, Spain;

Minist Hlth, Child Dev Ctr, Mahe, Seychelles;

Univ Udine, Dept Med & Biol Sci, Via Colugna 50, I-33100 Udine, Italy;

Univ Udine, Dept Med & Biol Sci, Via Colugna 50, I-33100 Udine, Italy;

Jozef Stefan Inst, Dept Environm Sci, Jamova Cesta 39, SI-1000 Ljubljana, Slovenia;

Jozef Stefan Inst, Dept Environm Sci, Jamova Cesta 39, SI-1000 Ljubljana, Slovenia;

Jozef Stefan Inst, Dept Environm Sci, Jamova Cesta 39, SI-1000 Ljubljana, Slovenia;

Univ Rochester, Med Ctr, Sch Med & Dent, 601 Elmwood Ave,Box 671, Rochester, NY 14642 USA;

Univ Rochester, Med Ctr, Sch Med & Dent, 601 Elmwood Ave,Box 671, Rochester, NY 14642 USA;

Univ Rochester, Med Ctr, Sch Med & Dent, 601 Elmwood Ave,Box 671, Rochester, NY 14642 USA;

Univ Rochester, Med Ctr, Sch Med & Dent, 601 Elmwood Ave,Box 671, Rochester, NY 14642 USA;

Karolinska Inst, Inst Environm Med, Nobels Vag 13, S-17177 Stockholm, Sweden;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
Methylmercury; Cognitive; CYP3A polymorphisms; Neurotoxicity; Birth cohort; Prenatal exposure;

机译：甲基汞认知CYP3A基因多态性神经毒性出生队列产前暴露;

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专利

1. Impact of prenatal methylmercury exposure on child neurodevelopment in the Faroe Islands [J] . Murata K, Dakeishi M 日本衛生学雑誌 . 2002,第3期

机译：产前甲基汞暴露对法罗群岛儿童神经发育的影响
2. Impact of prenatal methylmercury exposure on child neurodevelopment in the Faroe Islands [J] . Murata K, Dakeishi M 日本衛生学雑誌 . 2002,第3期

机译：产前甲基汞暴露对法罗群岛儿童神经发育的影响
3. Impact of prenatal methylmercury exposure on child neurodevelopment in the Faroe Islands [J] . Murata K, Dakeishi M 日本衛生学雑誌 . 2002,第3期

机译：产前甲基汞暴露对Faroe群岛儿童神经发作的影响
4. Understanding the Associations between Prenatal Dentine Manganese Exposure and Neurodevelopment through the Fusion of Multitask MRI Data [C] . Yuri Levin-Schwartz, Erik de Water, Megan Horton, Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2018

机译：通过多任务MRI数据融合了解产前牙本质锰暴露与神经发育之间的关联
5. Prenatal exposure to agricultural pesticides and neurodevelopment in children aged 2-5 [D] . Shelton, Janie Faye 2012

机译：2-5岁儿童的产前暴露于农业杀虫剂和神经发育
6. CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment [O] . Sabrina Llop, Van Tran, Ferran Ballester, -1

机译：CYP3A基因与产前甲基汞暴露与神经发育的关系
7. CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment [O] . Llop Sabrina, Tran Van, Ballester Ferran, 2017

机译：CYP3A基因与产前甲基汞的关系接触和神经发育

CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment

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